February 16^th at 12:00
on-site event
Presidentti auditorium, BioCity

Dr. Simon Yona, Hebrew University, Israel
Human mononuclear phagocyte kinetics in health and disease
host: Alexander Mildner (almild@utu.fi)

Coffee and sandwich served at 11:45

Six students and early-career postdocs are welcome to have a lunch in restaurant Mauno and discuss with Prof. Yona after the seminar. This is a great possibility to learn hosting skills in friendly environment and create connections for future. Every student are welcome to join, in spite of which research group they belong to. BioCity Turku will offer the lunch.

If you got interested, please send an email to biocityturku@bioscience.fi

Inflammation is an organism’s defensive response to foreign bodies and injury. While this is beneficial, it can go into disarray resulting in tissue damage and the development of chronic inflammatory conditions – including arthritis, fibrosis, multiple sclerosis etc. The research group of Prof. Yona is interested in cells of the mononuclear phagocyte system, a group of white blood cells that play an important role in the body’s immune response. In the lab their research focuses on monocyte, DC and macrophage dynamics and function under steady state and during disease to gain insights into how these cells are regulated and regulate physiological and pathological processes. This will enable the rational development of new treatments, based on a clearer understanding of how the body responds to inflammation.

Selected publications

Saba Y, Aizenbud I, Matanes D, Koren N, Barel O, Zubeidat K, Capucha T, David E, Eli-Berchoer L, Stoitzner P, Wilensky A, Amit I, Czerninski R, Yona S, Hovav AH. 2022. Early antitumor activity of oral Langerhans cells is compromised by a carcinogen. Proc Natl Acad Sci U S A. 119:e2118424119

Patel AA, Ginhoux F, Yona S. 2021. Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease. Immunology. 163:250-261

Guilliams M, Mildner A, Yona S. 2018. Developmental and Functional Heterogeneity of Monocytes. Immunity. 49:595-613

Patel AA, Zhang Y, Fullerton JN, Boelen L, Rongvaux A, Maini AA, Bigley V, Flavell RA, Gilroy DW, Asquith B, Macallan D, Yona S. 2017. The fate and lifespan of human monocyte subsets in steady state and systemic inflammation. J Exp Med. 214:1913-1923

General information

• You can download all spring 2023 FoS-seminars in your calendar from here: https://seafile.utu.fi/d/4a0b831f23ef420786b0/
• Registration is not needed for the on-site seminars
• Participation list is circulated in the audience
• If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars, please print out this seminar diary and after the seminar ask the BioCity coordinator to sign it
• Please note that any audio or video recording of the seminars is strictly forbidden.