April 13th at 10:15 and April 14th at 10:15
on-site event
Auditorium Pha1, Pharmacity

Professor Seamus Martin from Trinity College, Dublin and Editor in Chief of FEBS Journal will visit us as an InFLAMES guest next week April 13th-14th. He will give two talks:

Publishing Talk on Thursday April 13th at 10.15, Auditorium Pha1:
‘How to choose a great scientific question and prepare your paper for publication: what I wish I knew years earlier’

Scientific Seminar Friday April 14th at 10.15, Auditorium Pha1:
‘Cell Death, Cell Stress and Inflammation: What doesn’t kill you makes you stranger’

Coffee and sandwiches will be served before at 10 before both seminars!

Postdocs and PhD students are welcome to join Professor Martin for lunch on Friday April 14th at 12. Sign up to Anna Aalto (anna.aalto@abo.fi) at the latest on Tuesday April 11th to get the details.

If you want to meet Professor Martin for project chats, please contact Annika Meinander (annika.meinander@abo.fi).

Professor Seamus Martin is the holder of the Smurfit Chair of Medical Genetics at Trinity College Dublin, Ireland. Martin has an international reputation in the field of programmed cell death, which plays a key role in the development and function of the immune system. His work is especially focused on the links between cell death, inflammation and cancer. He is also a co-author of the 11th, 12th and 13th editions of the major Immunology textbook ‘Essential Immunology’ and is Editor-in-Chief of The FEBS Journal, a leading Life Sciences journal.

https://www.tcd.ie/Genetics/research/martins/
https://www.tcd.ie/research/profiles/?profile=martinsj

Some recent publications
Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement.
Sullivan GP, Davidovich P, Muñoz-Wolf N, Ward RW, Hernandez Santana YE, Clancy DM, Gorman A, Najda Z, Turk B, Walsh PT, Lavelle EC, Martin SJ.
Science Immunol. 2022 Dec 23;7(78):eade5728.

IL-1α and IL-36 Family Cytokines Can Undergo Processing and Activation by Diverse Allergen-Associated Proteases.
Frezza V, Najda Z, Davidovich P, Sullivan GP, Martin SJ.
Frontiers in Immunol. 2022 Jun 30;13:879029.

TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation.
Sullivan GP, O’Connor H, Henry CM, Davidovich P, Clancy DM, Albert ML, Cullen SP, Martin SJ.
Developmental Cell. 2020 Mar 23;52(6):714-730.e5.

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing.
Clancy DM, Sullivan GP, Moran HBT, Henry CM, Reeves EP, McElvaney NG, Lavelle EC, Martin SJ.
Cell Reports. 2018 Mar 13;22(11):2937-2950.

Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases.
Sullivan GP, Henry CM, Clancy DM, Mametnabiev T, Belotcerkovskaya E, Davidovich P, Sura-Trueba S, Garabadzhiu AV, Martin SJ.
Cell Death and Disease. 2018 Mar 7;9(3):378.

An Inflammatory Perspective on Necroptosis.
Kearney CJ, Martin SJ.
Molecular Cell. 2017 Mar 16;65(6):965-973.

Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation.
Henry CM, Martin SJ.
Molecular Cell. 2017 Feb 16;65(4):715-729.e5.

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines.
Henry CM, Sullivan GP, Clancy DM, Afonina IS, Kulms D, Martin SJ.
Cell Reports. 2016 Feb 2;14(4):708-722.