Mark S. Johnson
Professor
Faculty of Science and Engineering
Åbo Akademy University
Research
My research team at the Structural Bioinformatics Laboratory (SBL) focuses on how biological molecules function to produce their biological consequences. Our team has broad expertise and hence applies multiple approaches to investigate different problems, primarily involving human proteins. Key approaches employed by us in our research are experimental structural biology (X-ray crystallography), structural bioinformatics (structure and molecular complex modeling), in silico screening for ligands and development of biologics, development and application of novel computational tools.
Our research is made in close cooperation with research groups investigating the biological problem primarily using wet-lab experimental approaches. Our main current problems focus on transcription factors in very early human development; kinases and their involvement in disease processes; integrins – evolution and roles in disease processes; engineering of enzymes for specific chemistries.
My research team at the Structural Bioinformatics Laboratory (SBL) focuses on how biological molecules function to produce their biological consequences. Our team has broad expertise and hence applies multiple approaches to investigate different problems, primarily involving human proteins. Key approaches employed by us in our research are experimental structural biology (X-ray crystallography), structural bioinformatics (structure and molecular complex modeling), in silico screening for ligands and development of biologics, development and application of novel computational tools.
Our research is made in close cooperation with research groups investigating the biological problem primarily using wet-lab experimental approaches. Our main current problems focus on transcription factors in very early human development; kinases and their involvement in disease processes; integrins – evolution and roles in disease processes; engineering of enzymes for specific chemistries.
