Tue Apr 15, 2025 at 19.00-19.45 Finland time (12pm – 12:45 pm EDT)

Online event

Dr. Robert Moulder, University of Turku: Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes affirms markers of disease

Join Zoom Meeting https://us02web.zoom.us/j/89411895420

Robert Moulder is a Senior Scientist at Turku Bioscience, a research centre jointly supported by the University of Turku and Åbo Akademi University in Turku, Finland.

He primarily focuses on mass spectrometry-based proteomics research related to type 1 diabetes and the characterization of T helper cell subtypes.He is first author on the recent Diabetologia paper: Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory

RECENT PAPER:  https://pubmed.ncbi.nlm.nih.gov/37537394/<https://www.google.com/url?q=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F37537394%2F&sa=D&ust=1744120380000000&usg=AOvVaw1cyd4GAR4KxBMeITmhPJBh

RESULTS from this paper : Eleven proteins had statistically significant associations with fasting C-peptide/glucose. Of these, apolipoprotein L1 and glutathione peroxidase 3 (GPX3) displayed the strongest positive and inverse associations, respectively. Changes in GPX3 levels during the first year after diagnosis indicated future fasting C-peptide/glucose levels. In addition, differences in the levels of 13 proteins were observed between the individuals with type 1 diabetes and the matched UFMs. These included GPX3, transthyretin, prothrombin, apolipoprotein C1 and members of the IGF family.