Dissertations
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2025
- Eccleshall, William: PIM kinases in luminal A breast cancer
 - Losenkova Mingeaud, Karolina: Adenosine metabolism in cancer: unveiling new therapeutic opportunities
 - Wang, Younghui: Delivery of Multiple Drugs and Mitochondria to regulate the Tumor Microenvironment for Cancer Treatment
 
2024
- Alzghool,Obada: Preclinical development of radiopharmaceuticals for Alzheimer’s disease: Biological evaluation of (S)-[18F]THK5117 and [11C]SMW139 PET tracers in the APP/PS1-21 mouse model of Alzheimer’s disease
 - van Asten, Jordy: Modeling mechano-regulated Notch signaling in arterial growth and remodeling
 - Bär,Sarah: Novel Imaging Approaches for the Detection of Hemodynamically Significant Coronary Artery Disease: Quantitative Flow Ratio and Artificial Intelligence-Based Ischemia Algorithm
 - Flinkman, Dani: Proteomic analysis of Parkinson’s disease mechanism and biomarkers
 - Hiltunen, Riina: Tutkimuksia yksityisen terveysmarkkinan kilpailusta
 - Hoppela, Erika: Metabolism, Morphology, and Effect of Fat Grafts – Studies on Fat Graft Browning and Therapeutic Use in the Prevention of Peritoneal Adhesions
 - Huhtinen, Olli: Advancing Antibody Engineering: Development of a Novel Bxb1 Landing Pad-Based Mammalian Display Platform for the ion of Biophysically Favorable Antibodies
 - Isomursu, Aleksi: Biomechanics of cancer cell motility
 - Jain, Shruti: Novel Circulatory Biomarkers for Ovarian Cancer Diagnosis – Nanoparticle based glycovariant assays
 - Kaivola, Jasmin: Biomechanical tumour matrix
 - Knuutila, Aapo: Characteristics of anti-pertussis toxin antibodies after vaccination and infection
 - Kujala, Iida: Hybrid PET/CTA imaging for coronary artery disease: Studies on the effect of sex and genetic factors on diagnosis and outcome
 - Mokhtary, Pardis: Characterization of human monoclonal antibodies against Neisseria gonorrhoeae and cognate antigen discovery
 - Nyström, Joel: Keratin Filaments as Regulators of Intracellular Organization and Metabolism in Colonocytes
 - Pekkarinen, Laura: Insulin sensitivity and endocannabinoid function as risk factors for obesity: Positron emission tomography studies of insulin sensitivity and CB1 receptors
 - Pylvänäinen, Joanna: Bioimage Analysis for Life Scientists : Tools for Live Cell Imaging
 - Rawand, Mustafa: Silica core@shell Nanoparticles for Biomedical Applications: A study in Pharmaceutical Sciences
 - Sharma, Mukund: Convergence of RAS and PP2A activities on chromatin repressor complexes
 - Suarez Rodriguez, Freddy: Vascular cells and mechanical signals. A study of the role of Jagged1 in vascular mechanosensing
 - Sucksdoff, Marcus: Smouldering inflammation in multiple sclerosis – A PET imaging study on prediction of disease progression and effects of treatment
 - Virta, Jenni: Positron emission tomography imaging of disease activity in atherosclerosis
 - Yan, Jiaqi: Precision Therapeutics: Harnessing Receptor-targeted and Dynamic DNA Nanotechnology
 - Zhou, Wenhui: Development of Novel Porous Nanomaterial-Based Drug Delivery Systems for Precision Cancer Treatment
 - Özliseli, Ezgi: Nanoparticle-aided delivery for tracking and controlling cell fate decisions in complex environments
 
2023
- Adossa, Nigatu: Computational approaches for single-cell omics and multi-omics data
 - Chakroborty, Deepankar: Novel tools for identification of oncogenic driver mutations
 - Faux Thomas: Computational methods for studying epigenomic regulation
 - Felix, Ines: Ontogeny and function of adipose tissue macrophages
 - Grönroos, Sofia: Long-term outcomes of laparoscopic sleeve gastrectomy vs. laparoscopic Roux-en-Y gastric bypass: Special focus on procedure selection, gastroesophageal reflux, and quality of life
 - Hartiala, Maria: Community-acquired pneumonia in children: Aetiology, clinical features, and complications
 - Hong, Ye: Evaluation of the relevance and impact of kinase dysfunction in neurological disorders through proteomics and phosphoproteomics bioinformatics
 - Kuusisto, Niina: Artifacts due to dental and maxillofacial restoration materials in cone beam computed tomography images
 - Lokka, Emmi: Foetal monocytes and their journey from liver to periphery: PLVAP marks the exit
 - Ma Xiaodong: Stimuli-Responsive Prodrug Nanomaterials for Combination Therapy of Cancer.
 - Mehmood, Arfa: Tools and strategies for RNA-sequencing data analysis
 - Miner,Maxwell: Emerging radiopharmaceuticals for PET-imaging gliomas. A multi-: radiopharmaceutical, camera, modality, model, and modelling assessment
 - Mohan Aravind Kumar: Regulation of inflammatory signalling by caspases and M1-linked ubiquitin chains in Drosophila melanogaster
 - Nagelli, Srikar: CIP2A is a critical DNA damage response protein that drives basal-like breast cancer
 - Patyra, Konrad: Novel molecular mechanisms of thyroid disorders: from human diseases to mouse models
 - Pöysti, Sakari: The Gut-pancreas axis in autoimmune diabetes.
 - Ranga, Vipin Specificity Determining Features at the Interface of Biomolecular Complexes as Regulators of Biological Functions
 - Riivari, Sini: Gingival cell attachment and cell adhesion complex formation on TiO2 coated zirconia and titanium
 - Rodprasert, Wiwat: Novel molecular mechanisms of thyroid disorders: from human diseases to mouse models
 - Sirkiä, Saara V: Physicochemical properties and characterization of bioceramics and bioactive glasses for bone repair
 - Smolander, Johannes: Cell type identification, differential expression analysis and trajectory inference in single-cell transcriptomics
 - Soto Veliz, Diosangeles: Printable Cell Growth Platform for the Assessment of Biomaterial-cell Interactions : A Focus on Patterns and Mineral Pigments
 - Viitala, Miro: Re-educating macrophages to activate antitumor immunity: One Clever Immunotherapy
 - Wang, Ning: Computational analysis of human genomic variants and lncRNAs from sequence data
 
2022
- Aalto, Anna: Met1-ubiquitination determines inflammatory signalling in Drosophila melanogaster
 - Ballo, Haitham: Advanced cardiac imaging of cardiac function and coronary artery disease
 - Haijanen, Jussi: Uncomplicated acute appendicitis – towards optimization of diagnostics, antibiotic management, and treatment costs
 - Haveri, Anu: Influenza vaccine induced antibody responses in relation to evolution of influenza A viruses
 - He, Felix: Interaction of filovirus proteins with RIG-I signaling pathways
 - Henriksen, Louise Scheutz: Impact of pre- and early postnatal life on adult male reproductive health
 - Hernandez-Perez, Sara: B Cell Activation and Antibody Responses – The role of vesicle trafficking and Rab GTPases
 - Islam, Khirul: Extracellular vesicle glycosylations as novel biomarkers of urological cancers: Nanoparticle-aided glycovariant assay to detect vesicles for the early detection of cancer
 - Jaakkola, Maria: Extracting information from high-throughput gene expression data with pathway analysis and deconvolution
 - Jokinen, Elmeri: Molecular dynamics and virtual screening approaches in drug discovery
 - Kantonen, Tatu: Brain opioid and endocannabinoid systems as risk factors for obesity. Positron emission tomography studies of μ-opioid and CB1 receptors with glucose uptake analysis
 - Kuutti, Katariina: Early prognostic factors of multiple sclerosis
 - Laajala, Essi: Multi-omics Analysis of Early Molecular Mechanisms of Type 1 Diabetes
 - Liu, Chang: Stimuli-Responsive Porous Nanoparticles for Controlled Drug Delivery and Gene Therapy
 - Mattila, Kalle: Novel prognostic factors for advanced melanoma and localized renal cell carcinoma
 - Moisio, Olli: Development of radiopharmaceuticals for PET imaging of Inflammation – VAP-1, FR-beta and CLEVER-1 as target molecules
 - Negi, Priyanka: Phage display based approach for identifying novel HDL particle binders: Recombinant HDL antibodies as novel diagnostic tool for risk assessment and monitoring of coronary artery disease
 - Pietilä, Sami: Data-independent acquisition mass spectrometry for the human gut microbiota proteome analysis
 - Pöyhönen, Heidi: Neurologiset jäännösoireet ovat tavallisia lapsena sairastetun aivotulehduksen jälkeen
 - Routila, Johannes: Molecular biomarkers in head and neck cancer: Evaluation of biomarkers in prognostication and radiotherapy response prediction
 - Runsala, Marika: Antigen processing and intracellular trafficking in B cells
 - Sarapulov, Alexey: B cell-mediated immunity and signal regulation. The roles of MIM/MTSS1 and IRF4
 - Seyednasrollah, Fatemeh: Machine Learning and Computational Methods to Identify Molecular and Clinical Markers for Complex Diseases – Case Studies in Cancer and Obesity
 - Tadayon, Sina: Role of Clever-1 in Leukocyte Trafficking and Inflammation
 - Taskinen, Maria: Actin- and adhesion-mediated regulation of cell states – from cancer to stem cells
 - Tiemeijer, Laura: Spatial Control of Angiogenesis by engineered patterns of Notch ligands
 - Toppala, Sini: Disturbances of glucose metabolism, cognitive decline, and neuroimaging changes related to Alzheimer’s disease
 - Vainio, Susanne: Experimental models of focal neuroinflammation – Efficacy assessment of pharmaceuticals of multiple sclerosis using PET imaging
 - Virtanen, Laura: Pathogenesis of LMNA-related dilated cardiomyopathy
 - Välikangas, Tommi: Enhanced label-free discovery proteomics through improved data analysis and knowledge enrichment
 
2021
- Ahinko, Mira: Computational cytochrome P450 mediated metabolism and virtual screening
 - Eichin, Dominik: Immunoregulatory roles of CD73 in lymphatic endothelial and myeloid cells
 - Gabriel, Michael: ENDOMET database – A means to identify novel diagnostic and prognostic tools for endometriosis
 - Gibreel, Mona: Fiber-reinforced implantretained overdentures: studies of their mechanical behavior and deformation in relation with attachment systems
 - Kaskikallio, Alar: The Effect of Vascular Brain Changes on Cognitive Function in Normal Aging, Mild Cognitive Impairment and Alzheimer’s Disease
 - Khan, Aftab: Fiber-reinforced composite with interpenetrating polymer network – Influence of shelf-life of the prepreg and the adhesive primer on interfacial adhesive strength of the composite to a resin luting material
 - Khan, Mohd Moin: Role of cancerous inhibitor of protein phosphatase 2A in the regulation of T-cell response
 - Kietz, Christa: Regulation of Host-Microbe Interactions and Inflammatory Signalling in Drosophila melanogaster
 - Kurkinen, Sami: Cavity-based negative images in molecular docking
 - Laurila, Sanna: Metabolic effects of the gastrointestinal hormone secretin with focus on brown adipose tissue
 - Lerche, Martina: Integrin activity regulation in mechanosensing: Integrin beta1 activity and extracellular matrix crosstalk
 - Lindgren, Noora: Early detection of Alzheimer’s disease – Twin study on episodic memory and imaging biomarkers of neuroinflammation and β-amyloid
 - Miihkinen, Mitro: Novel insights into filopodia function – A focus on integrin and F-actin regulation
 - Mäkinen, Erika: Photoinitiated curing of orthodontic adhesive resin
 - Sippola, Suvi: Uncomplicated Acute Appendicitis – Studies on Diagnosis and Treatment Outcomes
 - Suomi, Tomi: Data analysis tools for mass spectrometry proteomics
 - Tamirat, Mahlet: The Dynamic Structural Effects of Activating ERBB Kinase Somatic Mutations
 - Tuisku, Jouni: Imaging of neuroinflammation in multiple sclerosis brain : a positron emission tomography and diffusion tensor imaging study
 - Tuokkola, Terhi: Magnetic resonance imaging In Alzheimer’s disease, mild cognitive impairment and normal aging : Multi-template tensor-based morphometry and visual rating
 - Viitanen, Riikka: Evaluation of 68Ga-labeled PET radiopharmaceuticals for imaging of αvβ3 integrin and vascular adhesion protein-1 in inflammation and cancer
 - Åstrand, Mia: Virulence and survival mechanisms in Borrelia and Klebsiella infections – a structural bioinformatics perspective
 
2020
- Basavarajappa, Santhosh: Surface dissolution and degradation of dental resin-based materials with special emphasis by the effects of solvent ethanol, dimethacrylate monomer resin and catalyst solution of ethylene glycol
 - Cisneros-Montalvo, Sheyla: Old acquaintances and new perspectives into testicular development and function
 - Elo, Petri: Preclinical evaluation of novel radiopharmaceuticals for positron emission tomography imaging of animal models of multiple sclerosis
 - Fair-Mäkelä, Ruth: Lymphatic endothelial cells regulate traffic in lymph nodes
 - Grönman, Maria: PET imaging of ischaemic myocardial injury and angiogenesis
 - Kilponen, Leeni: Bonding of orthodontic brackets to enamel: Studies on the clinical outcome of bracket bonding and approaches to increase the bond strength of the adhesive interface
 - Konki, Mikko: Implementation of modern methods to identify DNA methylation marks for episodic memory impairment and Alzheimer’s disease
 - Korhonen, Laura: Prenatal stress, genomic variations and recurrent respiratory tract infections – the FinnBrain Birth Cohort Study
 - Käkelä, Meeri: Gallium-68 radiolabeling of biomolecules for positron emission tomography with special reference to imaging of inflammation and bone
 - Latva-Rasku, Aino: Regulators of central and peripheral insulin sensitivity in humans
 - Mäkinen, Marjaana: Vitamin D and type 1 diabetes : Serum 25- hydroxyvitamin D contentreations and risk of type 1 diabetes in children
 - Rebelos, Eleni: Novel aspects of insulin resistance: focus on the brain. Studies using positron emission tomography
 - Salomaa, Siiri: Crosstalk between cell adhesion and the actin cytoskeleton
 - Shetty, Ankitha: Understanding regulatory mechanisms of human T-helper 17 differentiation
 - Stenström, Iida: Myocardial blood flow and coronary anatomy in suspected obstructive coronary artery disease – a hybrid imaging study
 - Ståhle, Mia: Molecular imaging and immunotherapy in atherosclerotic cardiovascular disease