Dissertations
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2023
- Chakroborty, Deepankar: Novel tools for identification of oncogenic driver mutations
- Faux Thomas: Computational methods for studying epigenomic regulation
- Nagelli, Srikar: CIP2A is a critical DNA damage response protein that drives basal-like breast cancer
- Patyra, Konrad: Novel molecular mechanisms of thyroid disorders: from human diseases to mouse models
- Pöysti, Sakari: The Gut-pancreas axis in autoimmune diabetes
- Ranga, Vipin Specificity Determining Features at the Interface of Biomolecular Complexes as Regulators of Biological Functions.
- Soto Veliz, Diosangeles: Printable Cell Growth Platform for the Assessment of Biomaterial-cell Interactions : A Focus on Patterns and Mineral Pigments
- Viitala, Miro: Re-educating macrophages to activate antitumor immunity: One Clever Immunotherapy
2022
- Aalto, Anna: Met1-ubiquitination determines inflammatory signalling in Drosophila melanogaster
- Ballo, Haitham: Advanced cardiac imaging of cardiac function and coronary artery disease
- Haijanen, Jussi: Uncomplicated acute appendicitis – towards optimization of diagnostics, antibiotic management, and treatment costs
- Haveri, Anu: Influenza vaccine induced antibody responses in relation to evolution of influenza A viruses
- He, Felix: Interaction of filovirus proteins with RIG-I signaling pathways
- Henriksen, Louise Scheutz: Impact of pre- and early postnatal life on adult male reproductive health
- Hernandez-Perez, Sara: B Cell Activation and Antibody Responses – The role of vesicle trafficking and Rab GTPases
- Islam, Khirul: Extracellular vesicle glycosylations as novel biomarkers of urological cancers: Nanoparticle-aided glycovariant assay to detect vesicles for the early detection of cancer
- Jaakkola, Maria: Extracting information from high-throughput gene expression data with pathway analysis and deconvolution
- Jokinen, Elmeri: Molecular dynamics and virtual screening approaches in drug discovery
- Kantonen, Tatu: Brain opioid and endocannabinoid systems as risk factors for obesity. Positron emission tomography studies of μ-opioid and CB1 receptors with glucose uptake analysis
- Kuutti, Katariina: Early prognostic factors of multiple sclerosis
- Laajala, Essi: Multi-omics Analysis of Early Molecular Mechanisms of Type 1 Diabetes
- Liu, Chang: Stimuli-Responsive Porous Nanoparticles for Controlled Drug Delivery and Gene Therapy
- Mattila, Kalle: Novel prognostic factors for advanced melanoma and localized renal cell carcinoma
- Moisio, Olli: Development of radiopharmaceuticals for PET imaging of Inflammation – VAP-1, FR-beta and CLEVER-1 as target molecules
- Negi, Priyanka: Phage display based approach for identifying novel HDL particle binders: Recombinant HDL antibodies as novel diagnostic tool for risk assessment and monitoring of coronary artery disease
- Pietilä, Sami: Data-independent acquisition mass spectrometry for the human gut microbiota proteome analysis
- Routila, Johannes: Molecular biomarkers in head and neck cancer: Evaluation of biomarkers in prognostication and radiotherapy response prediction
- Runsala, Marika: Antigen processing and intracellular trafficking in B cells
- Sarapulov, Alexey: B cell-mediated immunity and signal regulation. The roles of MIM/MTSS1 and IRF4
- Seyednasrollah, Fatemeh: Machine Learning and Computational Methods to Identify Molecular and Clinical Markers for Complex Diseases – Case Studies in Cancer and Obesity
- Tadayon, Sina: Role of Clever-1 in Leukocyte Trafficking and Inflammation
- Taskinen, Maria: Actin- and adhesion-mediated regulation of cell states – from cancer to stem cells
- Tiemeijer, Laura: Spatial Control of Angiogenesis by engineered patterns of Notch ligands
- Vainio, Susanne: Experimental models of focal neuroinflammation – Efficacy assessment of pharmaceuticals of multiple sclerosis using PET imaging
- Virtanen, Laura: Pathogenesis of LMNA-related dilated cardiomyopathy
- Välikangas, Tommi: Enhanced label-free discovery proteomics through improved data analysis and knowledge enrichment
2021
- Ahinko, Mira: Computational cytochrome P450 mediated metabolism and virtual screening
- Eichin, Dominik: Immunoregulatory roles of CD73 in lymphatic endothelial and myeloid cells
- Gabriel, Michael: ENDOMET database – A means to identify novel diagnostic and prognostic tools for endometriosis
- Gibreel, Mona: Fiber-reinforced implantretained overdentures: studies of their mechanical behavior and deformation in relation with attachment systems
- Kaskikallio, Alar: The Effect of Vascular Brain Changes on Cognitive Function in Normal Aging, Mild Cognitive Impairment and Alzheimer’s Disease
- Khan, Aftab: Fiber-reinforced composite with interpenetrating polymer network – Influence of shelf-life of the prepreg and the adhesive primer on interfacial adhesive strength of the composite to a resin luting material
- Khan, Mohd Moin: Role of cancerous inhibitor of protein phosphatase 2A in the regulation of T-cell response
- Kietz, Christa: Regulation of Host-Microbe Interactions and Inflammatory Signalling in Drosophila melanogaster
- Kurkinen, Sami: Cavity-based negative images in molecular docking
- Laurila, Sanna: Metabolic effects of the gastrointestinal hormone secretin with focus on brown adipose tissue
- Lerche, Martina: Integrin activity regulation in mechanosensing: Integrin beta1 activity and extracellular matrix crosstalk
- Lindgren, Noora: Early detection of Alzheimer’s disease – Twin study on episodic memory and imaging biomarkers of neuroinflammation and β-amyloid
- Miihkinen, Mitro: Novel insights into filopodia function – A focus on integrin and F-actin regulation
- Mäkinen, Erika: Photoinitiated curing of orthodontic adhesive resin
- Sippola, Suvi: Uncomplicated Acute Appendicitis – Studies on Diagnosis and Treatment Outcomes
- Suomi, Tomi: Data analysis tools for mass spectrometry proteomics
- Tamirat, Mahlet: The Dynamic Structural Effects of Activating ERBB Kinase Somatic Mutations
- Tuisku, Jouni: Imaging of neuroinflammation in multiple sclerosis brain : a positron emission tomography and diffusion tensor imaging study
- Tuokkola, Terhi: Magnetic resonance imaging In Alzheimer’s disease, mild cognitive impairment and normal aging : Multi-template tensor-based morphometry and visual rating
- Viitanen, Riikka: Evaluation of 68Ga-labeled PET radiopharmaceuticals for imaging of αvβ3 integrin and vascular adhesion protein-1 in inflammation and cancer
- Åstrand, Mia: Virulence and survival mechanisms in Borrelia and Klebsiella infections – a structural bioinformatics perspective
2020
- Basavarajappa, Santhosh: Surface dissolution and degradation of dental resin-based materials with special emphasis by the effects of solvent ethanol, dimethacrylate monomer resin and catalyst solution of ethylene glycol
- Cisneros-Montalvo, Sheyla: Old acquaintances and new perspectives into testicular development and function
- Elo, Petri: Preclinical evaluation of novel radiopharmaceuticals for positron emission tomography imaging of animal models of multiple sclerosis
- Fair-Mäkelä, Ruth: Lymphatic endothelial cells regulate traffic in lymph nodes
- Grönman, Maria: PET imaging of ischaemic myocardial injury and angiogenesis
- Kilponen, Leeni: Bonding of orthodontic brackets to enamel: Studies on the clinical outcome of bracket bonding and approaches to increase the bond strength of the adhesive interface
- Konki, Mikko: Implementation of modern methods to identify DNA methylation marks for episodic memory impairment and Alzheimer’s disease
- Korhonen, Laura: Prenatal stress, genomic variations and recurrent respiratory tract infections – the FinnBrain Birth Cohort Study
- Käkelä, Meeri: Gallium-68 radiolabeling of biomolecules for positron emission tomography with special reference to imaging of inflammation and bone
- Latva-Rasku, Aino: Regulators of central and peripheral insulin sensitivity in humans
- Rebelos, Eleni: Novel aspects of insulin resistance: focus on the brain. Studies using positron emission tomography
- Salomaa, Siiri: Crosstalk between cell adhesion and the actin cytoskeleton
- Shetty, Ankitha: Understanding regulatory mechanisms of human T-helper 17 differentiation
- Stenström, Iida: Myocardial blood flow and coronary anatomy in suspected obstructive coronary artery disease – a hybrid imaging study
- Ståhle, Mia: Molecular imaging and immunotherapy in atherosclerotic cardiovascular disease