BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:192@inflames.utu.fi DTSTART;TZID=Europe/Helsinki:20221004T110000 DTEND;TZID=Europe/Helsinki:20221004T120000 DTSTAMP:20230120T083320Z URL:https://inflames.utu.fi/events/inflames-visiting-professor-career-talk -aled-clayton/ SUMMARY:InFLAMES Visiting Professor Career Talk: Aled Clayton DESCRIPTION:Dear All\,\n\n\n\nWelcome to the Career Talk by InFLAMES Visiti ng Professor Aled Clayton! The talk is held on Tuesday October 4th at 11 i n Medisiina D Lauren 2.\n\nCoffee\, tea and sandwiches are served before t he seminar.\n\nInFLAMES also organizes an informal lunch meeting for early career scientists with Professor Clayton immediately after his career tal k at 12 in Medisiina D Blokki 1. Please register separately for this event here: https://link.webropol.com/s/lunch-aled-clayton\n\n \;\n\nAbout Professor Clayton:\n\nProf. Clayton established the first group focused on investigating the roles of extracellular vesicles (exosomes) in the UK. T he group has published highly cited articles in relation to vesicles\, the ir roles in subverting immune responses\, in controlling the cancer microe nvironment and as potential disease biomarkers. He has published some of t he seminal articles of the EV field with a h-index of 45 (>\;18 000 cita tions).\n\nHe is interested in understanding the mechanisms by which vesic le biogenesis and secretion is controlled\, and the impact such vesicles h ave on the development and progression of cancer\; particularly focusing o n prostate cancer. Developing tools and assays to quantify nano-vesicles i n biological fluid specimens is also an important aspect of the group's ac tivities.\n\nAlthough his main focus is in cancer biology\, he collaborate s broadly with researchers in Cardiff\, including those in the schools of dentistry\, engineering  and optometry\, and interacts with other Univers ities on aspects including cardiovascular disease\, neurodegenerative dise ases and other conditions that impact society in significant ways.\n\nhttp s://www.cardiff.ac.uk/people/view/122903-clayton-aled\n\nhttps://scholar.g oogle.co.uk/citations?user=pgDjFGcAAAAJ&\;hl=en\n\n \;\n\nFew selec ted publications:\n\nConnolly\, K. D. et al. 2015. Characterisation of adi pocyte-derived extracellular vesicles released pre- and post-adipogenesis. Journal of Extracellular Vesicles 4(s1)\, article number: 29159. (10.3402 /jev.v4.29159)\n\nBeltrami\, C. et al. 2015. Stabilization of urinary micr oRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1(2)\, pp. 151-166. (10.3390/ncrna1020151)\n\nSalimu\, J.\, Spary\, L. K. \, Al-Taei\, S.\, Clayton\, A.\, Mason\, M. D.\, Staffurth\, J. and Tabi\, Z. 2015. Cross-Presentation of the Oncofetal Tumor Antigen 5T4 from Irrad iated Prostate Cancer Cells—A Key Role for Heat-Shock Protein 70 and Rec eptor CD91. Cancer Immunology Research 3(6)\, pp. 678-688. (10.1158/2326-6 066.CIR-14-0079)\n\nWebber\, J. P.\, Yeung\, V. and Clayton\, A. 2015. Ext racellular vesicles as modulators of the cancer microenvironment. Seminars in Cell and Developmental Biology 40\, pp. 27-34. (10.1016/j.semcdb.2015. 01.013)\n\nWelton\, J. L.\, Webber\, J. P.\, Botos\, L.\, Jones\, M. and C layton\, A. 2015. Ready-made chromatography columns for extracellular vesi cle isolation from plasma. Journal of Extracellular Vesicles 4\, article n umber: 27269. (10.3402/jev.v4.27269)\n\nKim\, D. et al. 2015. EVpedia: a c ommunity web portal for extracellular vesicles research. Bioinformatics 31 (6)\, pp. 933-939. (10.1093/bioinformatics/btu741)\n\nChowdhury\, R.\, Web ber\, J. P.\, Gurney\, M.\, Mason\, M. D.\, Tabi\, Z. and Clayton\, A. 201 5. Cancer exosomes trigger mesenchymal stem cell differentiation into pro- angiogenic and pro-invasive myofibroblasts. Oncotarget 6(2)\, pp. 715-731. (10.18632/oncotarget.2711)\n\nWebber\, J. P. et al. 2015. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 3 4(3)\, pp. 290-302. (10.1038/onc.2013.560)\n\n \;\n\n \;\n\n \ ; ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/2022/ 09/Aled_color_2.png END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:DAYLIGHT DTSTART:20220327T040000 TZOFFSETFROM:+0200 TZOFFSETTO:+0300 TZNAME:EEST END:DAYLIGHT END:VTIMEZONE END:VCALENDAR