BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:283@inflames.utu.fi DTSTART;TZID=Europe/Helsinki:20231023T120000 DTEND;TZID=Europe/Helsinki:20231023T130000 DTSTAMP:20231017T123522Z URL:https://inflames.utu.fi/events/inflames-seminar-professor-steffen-jung / SUMMARY:[CANCELED]InFLAMES Seminar by Professor Steffen Jung: Macrophages & Monocytes revisited - Origins do matter DESCRIPTION:\n\nWhen: 23.10.2023 at 12.00-13.00\n\nWhere: Presidentti-audit orium\, Visitor Center Joki\n\nSteffen Jung. Professor at the Department o f Immunology\, Weizmann Institute of Science\, Rehovot\, Israel.\nMacropha ges &\; Monocytes revisited - Origins do matter \n\nE-mail: s.jung@weiz mann.ac.il\n\nWebsite: https://www.weizmann.ac.il/dept/irb/jung/\n\n \ ;\n\nAbout the lecturer:\n\nBorn in Homburg\, Germany\, Steffen Jung start ed his academic journey at the University of Bonn and later pursued his Ph .D. in Cologne\, under the guidance of Andreas Radbruch at the Institute o f Genetics headed by Klaus Rajewsky. His research focused on using gene ta rgeting technology to identify control elements in immunoglobulin class sw itch recombination.\n\nAfter completing his Ph.D.\, Steffen continued his studies in Israel\, joining Yinon Ben-Neriah's lab at the Lautenberg Cente r (Hebrew University) to explore transcription factors and kinases in T ce ll signaling. He then moved to New York for a post-doc at the Skirball Ins titute for Molecular Pathogenesis\, NYU Medical Center\, where he concentr ated on the chemokine receptor CX3CR1 and its ligand CX3CL1/fractalkine\, creating CX3CR1gfp reporter mice.\n\nIn 2002\, Steffen returned to Israel\ , becoming a faculty member in the Department of Immunology at the Weizman n Institute\, eventually achieving tenure and full professorship. His curr ent research focuses on understanding mononuclear phagocytes\, including m onocytes\, DCs\, and macrophages. His team employs cutting-edge techniques such as intra-vital imaging\, gene ablation\, and genomic analysis to stu dy these cells in health and disease contexts. Recent work explores monocy te-derived intestinal macrophages\, brain macrophages (including microglia and CNS-border associated macrophages)\, and their roles in metabolic dis orders.\n\nPresentative publications:\n\nPerivascular cells induce microgl ial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease \, De Schepper S.\, Ge J. Z.\, Crowley G. et al. (20 23) Nature Neuroscience. 26\, 3\, p. 406-415\n\nDistinct spatiotemporal fe atures of microglia and monocyte-derived macrophages in glioma \, Banerjee K.\, Ratzabi A.\, Caspit I. M.\, Ganon O.\, Blinder P.\, Jung S. &\; S tein R. (2023) European Journal of Immunology. e2250161.\n\nCognate microg lia–T cell interactions shape the functional regulatory T cell pool in e xperimental autoimmune encephalomyelitis pathology \, Haimon Z.\, Frumer G. R.\, Kim J. et al. (2022) Nature Immunology.\n\nA Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages \, Kim J.\, Kolesnikov M.\, Peled-Hajaj S. et al. (2021) Immunity. 54\, 1\, p. 1 76-190 ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/Steff en_Jung.jpg END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:DAYLIGHT DTSTART:20230326T040000 TZOFFSETFROM:+0200 TZOFFSETTO:+0300 TZNAME:EEST END:DAYLIGHT END:VTIMEZONE END:VCALENDAR