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UID:148@inflames.utu.fi
DTSTART;TZID=Europe/Helsinki:20220301T140000
DTEND;TZID=Europe/Helsinki:20220301T150000
DTSTAMP:20230120T083246Z
URL:https://inflames.utu.fi/events/immunology-seminar-heikki-hyoty/
SUMMARY:Immunology Seminar\, Heikki Hyöty
DESCRIPTION:&nbsp\;\n\n\n\nImmunology Seminar\n\nMarch 1st at 14:00 – 15:
 00\nVirtual event\n\nHeikki Hyöty\, Tampere University\nType 1 Diabetes\,
  Enterovirus and Prospects of Vaccine Development\n\nHost: Riitta Lahesmaa
  (rilahes@utu.fi)\n\nRegistration latest Feb 28 at: https://link.webropols
 urveys.com/S/64C9EC43374D8B69\nZoom link and iCalendar invitation to join 
 the online event will be sent to all registered participants one day befor
 e the event.\n\nImmunology seminar series is jointly organised by the Finn
 ish Society for Immunology\, InFLAMES Flagship and Turku Bioscience. For f
 urther information contact Anne Lahdenperä (ankahy@utu.fi) or Riitta Lahe
 smaa (rilahes@utu.fi)\, University of Turku.\n\n&nbsp\;\n\nDr. Heikki Hyö
 ty is Professor of Virology at Tampere University\, Faculty of Medicine an
 d Health Technology since 2013. Prof. Hyöty has received his PhD in virol
 ogy in 1989. He has served as Professor of Biomedicine and Virology at Uni
 versity of Tampere prior to his current position. Prof. Hyöty leads a vir
 ology group that studies the role of viruses and other microbes in immune-
 mediated diseases including type 1 diabetes\, asthma\, allergy and celiac 
 disease. The group has studied  microbe-disease associations in prospecti
 ve cohorts and translated innovations to develop new treatments and better
  diagnostics. One major initiative is the project developing an enteroviru
 s vaccine that could prevent severe enterovirus diseases and type 1 diabet
 es. This project has generated a vaccine against Coxsackie B viruses which
  have been linked to type 1 diabetes.\n\nProfessor Hyöty is coordinator o
 f four EU funded projects\, and has 422 original articles and altogether n
 ine patents/patent applications.\n\nSelected publications:\n\n 	Sioofy-Kho
 jine AB\, Lehtonen J\, Nurminen N\, Laitinen OH\, Oikarinen S\, Huhtala H\
 ,  Pakkanen O\, Ruokoranta T\, Hankaniemi MM\, Toppari J\, Vähä-Mäkil
 ä M\, Ilonen J\, Veijola R\, Knip M\, Hyöty H. Coxsackievirus B infectio
 ns are associated with the initiation of insulin-driven autoimmunity that 
 progress to type 1 diabetes. Diabetologia 6:1193-1202\, 2018.\n 	Hyöty H\
 , Leon F\, Knip M. Developing a vaccine for Type 1 diabetes by targeting c
 oxsackievirus B. Expert Rev Vaccines. 17(12):1071-1083\, 2018.\n 	Vehik K\
 , Lynch KF\, Wong MC\, Tian X\, Ross MC\, Gibbs RA\, Ajami NJ\, Petrosino 
 JF\,  Rewers M\, Toppari J\, Ziegler AG\, She JX\, Lernmark A\, Akolkar B
 \, Hagopian WA\, Schatz DA\, Krischer JP\, Hyöty H\, Lloyd RE\, and the T
 EDDY Study Group. Prospective virome analyses reveals prolonged enteroviru
 s B shedding precedes islet autoimmunity in children at increased genetic 
 risk for type 1 diabetes. Nat Med. 25(12):1865-1872\, 2019.\n 	Stone VM\, 
 Butrym M\, Hankaniemi MM\, Sioofy-Khojine A-B\, Hytönen VP\, Hyöty H\, F
 lodström-Tullberg M. Coxsackievirus B vaccines prevent infection-accelera
 ted diabetes in NOD mice and have no disease-inducing effect. Diabetes 70(
 12):2871-2878\, 2021.\n 	Oikarinen S\, Krogvold L\, Edwin B\, Buanes T\, K
 orsgren O\, Laiho JE\, Oikarinen M\, Ludvigsson J\, Skog O\, Anagandula M\
 , Frisk G\, Hyöty H*\, Dahl-Jørgensen K*. Characterisation of enteroviru
 s RNA detected in the pancreas and other specimens of live patients with n
 ewly diagnosed type 1 diabetes in the DiViD study. Diabetologia 64(11):249
 1-2501\, 2021.\n
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