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UID:473@inflames.utu.fi
DTSTART;TZID=Europe/Helsinki:20260416T100000
DTEND;TZID=Europe/Helsinki:20260416T110000
DTSTAMP:20260416T062359Z
URL:https://inflames.utu.fi/events/guest-seminar-by-professor-jo-van-ginde
 racther-epigenetic-imprinting-of-monocytes-and-tissue-resident-macrophages
 -by-infectious-disease-and-cancer/
SUMMARY:Guest seminar by Professor Jo Van Ginderachter: Epigenetic imprinti
 ng of monocytes and tissue-resident macrophages by infectious disease and 
 cancer
DESCRIPTION:\n\nWelcome to the guest seminar by Professor Jo Van Ginderacht
 er!\n\nSpeaker: Professor Jo Van Ginderachter\, Brussels Center for Immuno
 logy\nTitle: Epigenetic imprinting of monocytes and tissue-resident macrop
 hages by infectious disease and cancer\nLocation: Lauren 2 lecture room\, 
 Medisiina D\nTime: April 16\, 10-11 am\nHost: InFLAMES Group Leader Maija 
 Hollmén\, MediCity Research Laboratory\, University of Turku\n\nCoffee/te
 e and sandwich will be served starting at 9:30.\n\nAbout the speaker:\n\nP
 rofessor Jo Van Ginderachter is Lab Director of the Myeloid Cell Immunolog
 y lab at VIB (Center for Inflammation Research) and of the Brussels Center
  for Immunology lab at Vrije Universiteit Brussel. He has a long-standing 
 expertise in macrophage biology\, tumour immunology and applications of na
 nobodies. He published over 100 peer-reviewed articles and 4 book chapters
  on these topics. Most of the grants of the Van Ginderachter lab are deali
 ng with the characterization of tumour-associated macrophages and dendriti
 c cells\, several of which deal with nanobody-mediated imaging or therapy.
 \n\nExample publications:\n\nDepleting IL1R2+ Tumor-Infiltrating Regulator
 y T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Ant
 i-PD-1 Immunotherapy.\nArnouk SM\, Kancheva D\, Van Damme H\, Courtoy GE\,
  Mora Barthelmess R\, Van Craenenbroeck J\, Lebegge E\, Elkrim Y\, Assaf N
 \, Heremans Y\, Murgaski A\, De Groof TWM\, Clappaert E\, Debraekeleer A\,
  Brughmans J\, Blancke G\, Kiss M\, Forsyth R\, Waelput W\, Boon L\, Devoo
 gdt N\, Stortelers C\, van Boxel N\, Dombrecht B\, Vereecke L\, Vincke C\,
  Raes G\, Laoui D\, Van Ginderachter JA.Cancer Res. 2025 Dec 1\;85(23):468
 1-4700. doi: 10.1158/0008-5472.CAN-24-3095.\n\nEpigenomic preconditioning 
 of peripheral monocytes determines their transcriptional response to the t
 umor microenvironment.\nKiss M\, Halasz L\, Hadadi E\, Berger WK\, Tzerpos
  P\, Poliska S\, Kancheva D\, Gabriel A\, Mora Barthelmess R\, Debraekelee
 r A\, Brughmans J\, Elkrim Y\, Martens L\, Saeys Y\, Daniel B\, Czimmerer 
 Z\, Laoui D\, Nagy L\, Van Ginderachter JA.Genome Med. 2025 Jul 23\;17(1):
 82. doi: 10.1186/s13073-025-01511-y.\n\nImaging of tumor-associated macrop
 hage dynamics during immunotherapy using a CD163-specific nanobody-based i
 mmunotracer.\nLauwers Y\, De Groof TWM\, Vincke C\, Van Craenenbroeck J\, 
 Jumapili NA\, Barthelmess RM\, Courtoy G\, Waelput W\, De Pauw T\, Raes G\
 , Devoogdt N\, Van Ginderachter JA.Proc Natl Acad Sci U S A. 2024 Dec 24\;
 121(52):e2409668121. doi: 10.1073/pnas.2409668121. Epub 2024 Dec 18.\n\nMa
 crophages are metabolically heterogeneous within the tumor microenvironmen
 t.\nGeeraerts X\, Fernández-Garcia J\, Hartmann FJ\, de Goede KE\, Marten
 s L\, Elkrim Y\, Debraekeleer A\, Stijlemans B\, Vandekeere A\, Rinaldi G\
 , De Rycke R\, Planque M\, Broekaert D\, Meinster E\, Clappaert E\, Bardet
  P\, Murgaski A\, Gysemans C\, Nana FA\, Saeys Y\, Bendall SC\, Laoui D\, 
 Van den Bossche J\, Fendt SM\, Van Ginderachter JA.Cell Rep. 2021 Dec 28\;
 37(13):110171. doi: 10.1016/j.celrep.2021.110171.
ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/thumb
 nailjo-van-.png
CATEGORIES:Events in English,Tapahtumat
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DTSTART:20260329T040000
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