BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:473@inflames.utu.fi DTSTART;TZID=Europe/Helsinki:20260416T100000 DTEND;TZID=Europe/Helsinki:20260416T110000 DTSTAMP:20260410T105054Z URL:https://inflames.utu.fi/events/guest-seminar-by-professor-jo-van-ginde racther-epigenetic-imprinting-of-monocytes-and-tissue-resident-macrophages -by-infectious-disease-and-cancer/ SUMMARY:Guest seminar by Professor Jo Van Ginderachter: Epigenetic imprinti ng of monocytes and tissue-resident macrophages by infectious disease and cancer DESCRIPTION:\n\nWelcome to the guest seminar by Professor Jo Van Ginderacht er!\n\nSpeaker: Professor Jo Van Ginderachter\, Brussels Center for Immuno logy\nTitle: Epigenetic imprinting of monocytes and tissue-resident macrop hages by infectious disease and cancer\nLocation: Lauren 2 lecture room\, Medisiina D\nTime: April 16\, 10-11 am\nHost: InFLAMES Group Leader Maija Hollmén\, MediCity Research Laboratory\, University of Turku\n\n \;\n \nAbout the speaker:\n\nProfessor Jo Van Ginderachter is Lab Director of t he Myeloid Cell Immunology lab at VIB (Center for Inflammation Research) a nd of the Brussels Center for Immunology lab at Vrije Universiteit Brussel . He has a long-standing expertise in macrophage biology\, tumour immunolo gy and applications of nanobodies. He published over 100 peer-reviewed art icles and 4 book chapters on these topics. Most of the grants of the Van G inderachter lab are dealing with the characterization of tumour-associated macrophages and dendritic cells\, several of which deal with nanobody-med iated imaging or therapy.\n\nExample publications:\n\nDepleting IL1R2+ Tum or-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct B oosts the Efficacy of Anti-PD-1 Immunotherapy.\nArnouk SM\, Kancheva D\, V an Damme H\, Courtoy GE\, Mora Barthelmess R\, Van Craenenbroeck J\, Lebeg ge E\, Elkrim Y\, Assaf N\, Heremans Y\, Murgaski A\, De Groof TWM\, Clapp aert E\, Debraekeleer A\, Brughmans J\, Blancke G\, Kiss M\, Forsyth R\, W aelput W\, Boon L\, Devoogdt N\, Stortelers C\, van Boxel N\, Dombrecht B\ , Vereecke L\, Vincke C\, Raes G\, Laoui D\, Van Ginderachter JA.Cancer Re s. 2025 Dec 1\;85(23):4681-4700. doi: 10.1158/0008-5472.CAN-24-3095.\n\nEp igenomic preconditioning of peripheral monocytes determines their transcri ptional response to the tumor microenvironment.\nKiss M\, Halasz L\, Hadad i E\, Berger WK\, Tzerpos P\, Poliska S\, Kancheva D\, Gabriel A\, Mora Ba rthelmess R\, Debraekeleer A\, Brughmans J\, Elkrim Y\, Martens L\, Saeys Y\, Daniel B\, Czimmerer Z\, Laoui D\, Nagy L\, Van Ginderachter JA.Genome Med. 2025 Jul 23\;17(1):82. doi: 10.1186/s13073-025-01511-y.\n\nImaging o f tumor-associated macrophage dynamics during immunotherapy using a CD163- specific nanobody-based immunotracer.\nLauwers Y\, De Groof TWM\, Vincke C \, Van Craenenbroeck J\, Jumapili NA\, Barthelmess RM\, Courtoy G\, Waelpu t W\, De Pauw T\, Raes G\, Devoogdt N\, Van Ginderachter JA.Proc Natl Acad Sci U S A. 2024 Dec 24\;121(52):e2409668121. doi: 10.1073/pnas.2409668121 . Epub 2024 Dec 18.\n\nMacrophages are metabolically heterogeneous within the tumor microenvironment.\nGeeraerts X\, Fernández-Garcia J\, Hartmann FJ\, de Goede KE\, Martens L\, Elkrim Y\, Debraekeleer A\, Stijlemans B\, Vandekeere A\, Rinaldi G\, De Rycke R\, Planque M\, Broekaert D\, Meinster E\, Clappaert E\, Bardet P\, Murgaski A\, Gysemans C\, Nana FA\, Saeys Y\ , Bendall SC\, Laoui D\, Van den Bossche J\, Fendt SM\, Van Ginderachter J A.Cell Rep. 2021 Dec 28\;37(13):110171. doi: 10.1016/j.celrep.2021.110171. ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/thumb nailjo-van-.png CATEGORIES:Events in English,Tapahtumat END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:DAYLIGHT DTSTART:20260329T040000 TZOFFSETFROM:+0200 TZOFFSETTO:+0300 TZNAME:EEST END:DAYLIGHT END:VTIMEZONE END:VCALENDAR