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UID:508@inflames.utu.fi
DTSTART;TZID=Europe/Helsinki:20261112T120000
DTEND;TZID=Europe/Helsinki:20261112T130000
DTSTAMP:20260930T063047Z
URL:https://inflames.utu.fi/events/frontiers-of-science-prof-miguel-soares
 /
SUMMARY:Frontiers of Science: Prof. Miguel Soares
DESCRIPTION:12th November at 12:00\nOnsite event\nin Presidentti auditorium
 \, BioCity\nAutumn 2026 poster\n\nProf. Miguel Soares\, Gulbenkian Institu
 te for Molecular Medicine\, Portugal\nMetabolic adaptation as a defence st
 rategy against infection\n\nHost: Antonio Sousa (aggode@utu.fi)\n\nCoffee 
 and sandwich served at 11:45\, first come first serve!\n\n&nbsp\;\n\nSix P
 hD researchers and early-career postdocs are welcome to have lunch and dis
 cuss with Prof. Soares after the seminar. This is a great possibility to l
 earn hosting skills in a friendly environment and create connections for f
 uture. Everyone is welcome to join\, BioCity Turku will offer the lunch.\n
 \nIf you got interested in joining the lunch\, please send an email to bio
 cityturku@bioscience.fi\n\n&nbsp\;\n\nProf. Soares’ lab studies how immu
 nity evolved in multicellular organisms as a means to limit the fitness co
 sts imposed by symbiotic interactions with different classes of microbes. 
 Resistance is a cardinal feature of immunity\, whereby soluble and cellula
 r components of the immune system sense and target pathogenic microorganis
 ms for containment\, destruction\, or expulsion. In addition\, multicellul
 ar organisms deploy another defense strategy\, referred to as disease tole
 rance\, which does not target microbes directly. This evolutionarily conse
 rved strategy relies on stress responses that rewire host energy metabolis
 m. At the Inflammation Laboratory\, researchers aim to identify and charac
 terize how these stress responses engage inter-organ communication process
 es that rewire energy metabolism in order to limit the fitness costs assoc
 iated with infections caused by different classes of microbes. The objecti
 ve is to provide a transformative understanding of host–microbe interact
 ions and their translational impact on the treatment of global infectious 
 diseases.\n\n&nbsp\;\n\nSelected publications\n\nSoares MP\, Jentho E. Age
 ing rewires the body's tolerance to infection. Nature. 2026 Feb\;650(8102)
 :558-559\n\nMartins R\, Blankehaus B\, Braza F\, Mesquita M\, Ventura P\, 
 Singh S\, Weis S\, Pires M\, Pagnotta S\, Wu Q\, Cardoso S\, Jentho E\, Fi
 gueiredo A\, Faísca P\, Nóvoa A\, Morais VA\, Wculek SK\, Sancho D\, Mal
 lo M\, Soares MP. Homeostatic control of energy metabolism by monocyte-der
 ived macrophages. EMBO J. 2026 Jan\;45(1):106-150\n\nFigueiredo A\, Rastog
 i ST\, …\, Portugal S\, Kurth F\, Elo LL\, Paul BD\, Martins R\, Soares 
 MP. A metabolite-based resistance mechanism against malaria. Science. 2025
  Jun 12\;388(6752):eadq6741.\n\nWu Q\, Sacomboio E\, Valente de Souza L\, 
 Martins R\, Kitoko J\, Cardoso S\, Ademolue TW\, Paixão T\, Lehtimäki J\
 , Figueiredo A\, Norden C\, Tharaux PL\, Weiss G\, Wang F\, Ramos S\, Soar
 es MP. Renal control of life-threatening malarial anemia. Cell Rep. 2023 F
 eb 28\;42(2):112057\n\nSingh S\, Bastos-Amador P\, Thompson JA\, Truglio M
 \, Yilmaz B\, Cardoso S\, Sobral D\, Soares MP. Glycan-based shaping of th
 e microbiota during primate evolution. Elife. 2021 May 19\;10:e67450.\n\n
  \n\nGeneral information\n\n 	Registration is not needed\, participation 
 list is circulated in the audience.\n 	If you are a student and later wish
  to get a certificate of attendance from the Frontier of Science seminars 
 (BKEM1020\; UTU)\, print out the seminar diary and after the seminar ask t
 he BioCity coordinator to sign it https://seafile.utu.fi/d/44a70f80ac1e46a
 9ad0a/\n 	Please note that any audio or video recording of the seminars is
  strictly forbidden.\n 	Autumn 2026 image credits to Samuel Svärd: Whole 
 mount immunofluorescent staining of the mouse retina. Image acquired on 3i
  CSU-W1 Spinning disk with 10x objective.\n
ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/soare
 s-thumbnail.jpg
CATEGORIES:Events in English
LOCATION:Presidentti auditorium\, BioCity\, Turku\, Finland
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