BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.4.5//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:509@inflames.utu.fi DTSTART;TZID=Europe/Helsinki:20261119T120000 DTEND;TZID=Europe/Helsinki:20261119T130000 DTSTAMP:20260930T063213Z URL:https://inflames.utu.fi/events/frontiers-of-science-prof-gwendalyn-ran dolph/ SUMMARY:Frontiers of Science: Prof. Gwendalyn Randolph DESCRIPTION:19th November at 12:00\nOnsite event\nin Presidentti auditorium \, BioCity\nAutumn 2026 poster\n\nProf. Gwendalyn Randolph\, WashU Medicin e\, USA\nThe 3 L’s converge: Lymphoid tissue\, lymphatics\, and lipoprot eins\n\nHost: Sirpa Jalkanen (sirjal@utu.fi)\n\nCoffee and sandwich served at 11:45\, first come first serve!\n\n \;\n\nSix PhD researchers and early-career postdocs are welcome to have lunch and discuss with Prof. Ran dolph after the seminar. This is a great possibility to learn hosting skil ls in a friendly environment and create connections for future. Everyone i s welcome to join\, BioCity Turku will offer the lunch.\n\nIf you got inte rested in joining the lunch\, please send an email to biocityturku@bioscie nce.fi\n\n \;\n\nGwendalyn J. Randolph is the Emil R. Unanue Distingui shed Professor in the Department of Immunology and Pathology at Washington University in St. Louis\, Missouri. Her  research focuses on the traffic king of immune cells and molecular cargo between tissues\, lymphatics\, an d distal organs\, and how these processes contribute to chronic inflammato ry disease. Her laboratory has defined how monocytes\, dendritic cells\, m acrophages\, and lipoproteins migrate through tissues and lymphatic vessel s in conditions such as atherosclerosis\, psoriasis\, Crohn’s disease\, and liver inflammation. By combining immunology\, imaging\, lineage tracin g\, and single-cell profiling approaches\, her lab has revealed mechanisms that regulate immune cell migration\, lymphatic transport\, and tissue-sp ecific macrophage specialization. More recently\, Gwendalyn Randolph’s r esearch has focused on the role of high-density lipoprotein (HDL) traffick ing in inflammation and tissue homeostasis. Her group demonstrated that ly mphatic and vascular transport pathways are critical for HDL movement betw een organs and identified a specialized form of intestine-derived HDL that protects the liver from inflammatory injury caused by microbial products. These findings provide new insight into the links between immunity\, meta bolism\, and inflammatory disease\, with potential translational applicati ons for cardiovascular\, intestinal\, and liver disorders. In parallel\, h er laboratory has trained numerous scientists who have gone on to establis h independent research laboratories worldwide.\n\n \;\n\nSelected publ ications\n\nShchukina I\, Rodriguez-Hernandez CJ\, …\, Kreisel D\, Rando lph GJ\, Artyomov MN. Inflammaging in aged tissues drives remodeling of th e CD8+ T cell compartment. Cell Rep. 2026 Apr 22\;45(5):117303\n\nKim A\, Alligood DM\, …\, Hegazy L\, Zinselmeyer BH\, Brestoff JR\, Martin CA\, Warner BW\, Elgendy B\, Randolph GJ. A Gut-Restricted Liver X Receptor Ago nist Ameliorates Liver Injury in Experimental Short Bowel Syndrome. Gastro enterology. 2026 May\;170(5):1017-1032\n\nErlich EC\, Alayo QA\, Kim A\, H an J\, Mintz RL\, Huckstep CG\, Ruiz HS\, Field RL\, Dunning TJ\, Saleh LS \, Hoofnagle MH\, Tumanov AV\, Guilak F\, Brestoff JR\, Czepielewski RS\, Randolph GJ. Distinct roles for B cell-derived LTα3 and LTα1β2 in TNF-m ediated ileitis. Nat Immunol. 2025 Oct\;26(10):1781-1793\n\nGallerand A\, Han J\, Ivanov S\, Randolph GJ. Mouse and human macrophages and their role s in cardiovascular health and disease. Nat Cardiovasc Res. 2024 Dec\;3(12 ):1424-1437\n\nHan J\, Gallerand A\, Erlich EC\, …\, Finlay CM\, Allen J E\, Jakubzick CV\, Else KJ\, Onufer EJ\, Zhang N\, Randolph GJ. Human sero us cavity macrophages and dendritic cells possess counterparts in the mous e with a distinct distribution between species. Nat Immunol. 2024 Jan\;25( 1):155-165\n\n \;\n\nGeneral information\n\n Registration is not need ed\, participation list is circulated in the audience.\n If you are a stu dent and later wish to get a certificate of attendance from the Frontier o f Science seminars (BKEM1020\; UTU)\, print out the seminar diary and afte r the seminar ask the BioCity coordinator to sign it https://seafile.utu.f i/d/44a70f80ac1e46a9ad0a/\n Please note that any audio or video recording of the seminars is strictly forbidden.\n Autumn 2026 image credits to Sa muel Svärd: Whole mount immunofluorescent staining of the mouse retina. I mage acquired on 3i CSU-W1 Spinning disk with 10x objective.\n\n \; ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/rando lph-thumbnail.jpg CATEGORIES:Events in English LOCATION:Presidentti auditorium\, BioCity\, Turku\, Finland X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=BioCity\, Turku\, Finland;X -APPLE-RADIUS=100;X-TITLE=Presidentti auditorium:geo:0,0 END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:STANDARD DTSTART:20261025T030000 TZOFFSETFROM:+0300 TZOFFSETTO:+0200 TZNAME:EET END:STANDARD END:VTIMEZONE END:VCALENDAR