BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.3.1//EN TZID:Europe/Helsinki X-WR-TIMEZONE:Europe/Helsinki BEGIN:VEVENT UID:245@inflames.utu.fi DTSTART;TZID=Europe/Helsinki:20230413T120000 DTEND;TZID=Europe/Helsinki:20230413T130000 DTSTAMP:20230317T142020Z URL:https://inflames.utu.fi/events/frontiers-of-science-prof-dipanjan-chow dhury-2/ SUMMARY:Frontiers of Science: Prof. Dipanjan Chowdhury DESCRIPTION:\n\nApril 13th at 12:00\non-site event\nPresidentti auditorium\ , BioCity\nSpring 2023 program\n\nProf. Dipanjan Chowdhury\, Dana-Farber C ancer Institute\, Harvard Medivcal School\, USA\nExpanding the scope of DN A repair factors- novel roles and applications\nhost: Jukka Westermarck (j ukwes@utu.fi)\n\nCoffee and sandwich served at 11:45\n\n \;\n\nSix stu dents and early-career postdocs are welcome to have a lunch in restaurant Mauno and discuss with Prof. Chowdhury after the seminar. This is a great possibility to learn hosting skills in friendly environment and create con nections for future. Every student are welcome to join\, in spite of which research group they belong to. BioCity Turku will offer the lunch.\n\nIf you got interested\, please send an email to biocityturku@bioscience.fi\n\ n \;\n\nThe Dipanjan Chowdhury Lab investigates how human cells sense and repair DNA damage. Loss of genome integrity due to DNA damage has long been established as a critical contributor to cancer and tumorigenesis. O ur work therefore focuses on how cells maintain genome integrity. Through genetic\, biochemical\, and proteomic approaches\, as well as collaboratio n with structural biologists\, computational biologists and mouse genetici sts\, we aim to achieve better understanding in cancer etiology and the de velopment of effective cancer diagnoses and therapies.Whether it is search ing for potential treatments to radiation exposure\, or the causes and tre atment of ovarian cancer\, we strive for research that makes a positive im pact.\n\n \;\n\nSelected publications\n\nIyer DR\, Harada N\, Clairmon t C\, Jiang L\, Martignetti D\, Nguyen H\, He YJ\, Chowdhury D\, D'Andrea AD. 2022. CCAR2 functions downstream of the Shieldin complex to promote do uble-strand break end-joining. Proc Natl Acad Sci U S A. 119:e2214935119\n \nda Costa AABA\, Chowdhury D\, Shapiro GI\, D'Andrea AD\, Konstantinopoul os PA. 2022. Targeting replication stress in cancer therapy. Nat Rev Drug Discov. in press\n\nPal S\, Kaplan JP\, Nguyen H\, Stopka SA\, Savani MR\, Regan MS\, Nguyen QD\, Jones KL\, Moreau LA\, Peng J\, Dipiazza MG\, Perc iaccante AJ\, Zhu X\, Hunsel BR\, Liu KX\, Alexandrescu S\, Drissi R\, Fil bin MG\, McBrayer SK\, Agar NYR\, Chowdhury D\, Haas-Kogan DA. 2022. A dru ggable addiction to de novo pyrimidine biosynthesis in diffuse midline gli oma. Cancer Cell. 40:957-972.e10\n\nFärkkilä A\, Gulhan DC\, Casado J\, Jacobson CA\, Nguyen H\, Kochupurakkal B\, Maliga Z\, Yapp C\, Chen YA\, S chapiro D\, Zhou Y\, Graham JR\, Dezube BJ\, Munster P\, Santagata S\, Gar cia E\, Rodig S\, Lako A\, Chowdhury D\, Shapiro GI\, Matulonis UA\, Park PJ\, Hautaniemi S\, Sorger PK\, Swisher EM\, D'Andrea AD\, Konstantinopoul os PA. 2020. Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer. Nat Commun. 11:1459\n\nSarek G\, K otsantis P\, Ruis P\, Van Ly D\, Margalef P\, Borel V\, Zheng XF\, Flynn H R\, Snijders AP\, Chowdhury D\, Cesare AJ\, Boulton SJ. 2019. CDK phosphor ylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. 57 5:523-527\n\n \;\n\nGeneral information\n\n You can download all spri ng 2023 FoS-seminars in your calendar from here: https://seafile.utu.fi/d/ 4a0b831f23ef420786b0/\n Registration is not needed for the on-site semina rs\n Participation list is circulated in the audience\n If you are a stu dent and later wish to get a certificate of attendance from the Frontier o f Science seminars\, please print out this seminar diary and after the sem inar ask the BioCity coordinator to sign it\n Please note that any audio or video recording of the seminars is strictly forbidden.\n\n \; ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/2023/ 01/chowdury-400x400-1.jpg CATEGORIES:Tapahtumat END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Helsinki X-LIC-LOCATION:Europe/Helsinki BEGIN:DAYLIGHT DTSTART:20230326T040000 TZOFFSETFROM:+0200 TZOFFSETTO:+0300 TZNAME:EEST END:DAYLIGHT END:VTIMEZONE END:VCALENDAR