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UID:239@inflames.utu.fi
DTSTART;TZID=Europe/Helsinki:20230525T120000
DTEND;TZID=Europe/Helsinki:20230525T130000
DTSTAMP:20230313T095005Z
URL:https://inflames.utu.fi/events/frontiers-of-science-pasi-a-janne/
SUMMARY:Frontiers of Science: Pasi A. Jänne
DESCRIPTION:\n\nFrontiers of Science\n\nMay 25th at 12:00\nOn-site event\nP
 residentti auditorium\, BioCity\nSpring 2023 program\n\nProf. Pasi Jänne\
 , Dana-Farber Cancer Institute\, Harvard Medical School\, USA\nChallenges 
 in molecularly targeted treatment of lung cancer\nHost: Klaus Elenius (kla
 ele@utu.fi)\n\nCoffee and sandwich served at 11:45\n\n&nbsp\;\n\nSix stude
 nts and early-career postdocs are welcome to have a lunch and discuss with
  Prof. Jänne after the seminar. This is a great possibility to learn host
 ing skills in friendly environment and create connections for future. Ever
 y student are welcome to join\, in spite of which research group they belo
 ng to. BioCity Turku will offer the lunch.\n\nIf you got interested\, plea
 se send an email to biocityturku@bioscience.fi\n\n&nbsp\;\n\nThe Jänne La
 b's research integrates bench-based studies with translational research an
 d clinical trials of novel therapeutic agents in patients with lung cancer
 . The Lab's main research interest centers on understanding and translatin
 g the therapeutic importance of oncogenic alterations found in lung cancer
 . Dr. Jänne is a translational thoracic medical oncologist at the Dana-Fa
 rber Cancer Institute and a professor of medicine at Harvard Medical Schoo
 l. He is the director of the Lowe Center for Thoracic Oncology and the sci
 entific co-director of the Belfer Center for Applied Cancer Sciences.\n\n&
 nbsp\;\n\nSelected publications\n\nHartmaier RJ\, Markovets AA\, Ahn MJ\, 
 … \, Cantarini M\, Jänne PA. 2023. Osimertinib + Savolitinib to Overcom
 e Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor-Mut
 ated\, MET-Amplified Non-Small Cell Lung Cancer: TATTON. Cancer Discov. 13
 :98-113\n\nKobayashi Y\, Oxnard GR\, Cohen EF\, Mahadevan NR\, … \, Shol
 l LM\, Jänne PA. 2022. Genomic and biological study of fusion genes as re
 sistance mechanisms to EGFR inhibitors. Nat Commun 13:5614\n\nTo C\, Beyet
 t TS\, Jang J\, Feng WW\, …\, Eck MJ\, Gray NS\, Jänne PA. 2022. An all
 osteric inhibitor against the therapy-resistant mutant forms of EGFR in no
 n-small cell lung cancer. Nat Cancer. 3:402-417\n\nKobayashi Y\, Chhoeu C\
 , Li J\, Price KS\, Kiedrowski LA\, Hutchins JL\, Hardin AI\, Wei Z\, Hong
  F\, Bahcall M\, Gokhale PC\, Jänne PA. 2022. Silent mutations reveal the
 rapeutic vulnerability in RAS Q61 cancers. Nature 603:335-342\n\nJänne PA
 \, Baik C\, Su WC\, Johnson ML\, Hayashi H\, Nishio M\, Kim DW\, Koczywas 
 M\, Gold KA\, Steuer CE\, Murakami H\, Yang JC\, Kim SW\, Vigliotti M\, Sh
 i R\, Qi Z\, Qiu Y\, Zhao L\, Sternberg D\, Yu C\, Yu HA. 2022. Efficacy a
 nd Safety of Patritumab Deruxtecan (HER3-DXd) in EGFR Inhibitor-Resistant\
 , EGFR-Mutated Non-Small Cell Lung Cancer. Cancer Discov. 12:74-89\n\n&nbs
 p\;\n\nGeneral information\n\n 	You can download all spring 2023 FoS-semin
 ars in your calendar from here: https://seafile.utu.fi/d/4a0b831f23ef42078
 6b0/\n 	Registration is not needed for the on-site seminars\n 	Participati
 on list is circulated in the audience\n 	If you are a student and later wi
 sh to get a certificate of attendance from the Frontier of Science seminar
 s\, please print out this seminar diary and after the seminar ask the BioC
 ity coordinator to sign it\n 	Please note that any audio or video recordin
 g of the seminars is strictly forbidden.\n\n&nbsp\;
ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/janne
 400x400.jpg
LOCATION:Presidentti auditorium\, BioCity\, Turku\, Finland
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