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UID:462@inflames.utu.fi
DTSTART;TZID=Europe/Helsinki:20251211T100000
DTEND;TZID=Europe/Helsinki:20251211T110000
DTSTAMP:20251128T110924Z
URL:https://inflames.utu.fi/events/career-talk-by-professor-marco-demaria/
SUMMARY:Career talk by Professor Marco Demaria
DESCRIPTION:When: December 11\, 2025 at 10:00–11:00\nWhere: Arje Scheinin
  lecture room\, Dentalia\nSpeaker: Professor Marco Demaria\, University of
  Groningen\, The Netherlands\nHost: Senior Research Fellow Gennadi Egutkin
 \n\nAbout Professor Demaria:\n\nDr Demaria is an associate professor in Ce
 llular Ageing and his research is focused towards identifying novel mechan
 isms and biomarkers associated to senescent cells. His laboratory has also
  a strong interest to characterize the pro-disease functions of senescent 
 cells induced during aging and by anti-cancer therapies. A major goal is t
 o exploit these findings for the development of rejuvenating interventions
 . In 2018 he co-founded a start-up company\, Cleara Biotech\, devoted to d
 evelop anti-senescence drugs.\n\nAbout Demaria lab:\n\n"We investigate how
  cellular senescence and other cell fates alter the tissue microenvironmen
 t and influence the aging process\, the capacity to recover from transient
  and chronic injury\, and the onset and progression of age-related patholo
 gy. We aim to understand basic molecular and cellular mechanisms\, and tar
 get such mechanisms to create therapies that enhance healthy longevity. Ou
 r multidisciplinary research spans basic\, translational\, and clinical ap
 proaches."\n\nSelected publications\n\nThe senescence-associated secretory
  phenotype and its physiological and pathological implications. Wang B\, H
 an J\, Elisseeff JH\, Demaria M. Nat Rev Mol Cell Biol. 2024 Dec\;25(12):9
 58-978. doi: 10.1038/s41580-024-00727-x. Epub 2024 Apr 23. PMID: 38654098\
 n\nTargeting anti-apoptotic pathways eliminates senescent melanocytes and 
 leads to nevi regression. Kohli J\, Ge C\, Fitsiou E\, Doepner M\, Branden
 burg SM\, Faller WJ\, Ridky TW\, Demaria M. Nat Commun. 2022 Dec 23\;13(1)
 :7923. doi: 10.1038/s41467-022-35657-9. PMID: 36564381\n\nSenescence and c
 ancer – role and therapeutic opportunities. Schmitt CA\, Wang B\, Demari
 a M. Nat Rev Clin Oncol. 2022 Oct\;19(10):619-636. doi: 10.1038/s41571-022
 -00668-4. Epub 2022 Aug 31. PMID: 36045302\n\nThe senescence-associated se
 cretory phenotype and its physiological and pathological implications. Wan
 g B\, Han J\, Elisseeff JH\, Demaria M. Nat Rev Mol Cell Biol. 2024 Dec\;2
 5(12):958-978. doi: 10.1038/s41580-024-00727-x. Epub 2024 Apr 23. PMID: 38
 654098\n\nTargeting anti-apoptotic pathways eliminates senescent melanocyt
 es and leads to nevi regression. Kohli J\, Ge C\, Fitsiou E\, Doepner M\, 
 Brandenburg SM\, Faller WJ\, Ridky TW\, Demaria M. Nat Commun. 2022 Dec 23
 \;13(1):7923. doi: 10.1038/s41467-022-35657-9. PMID: 36564381\n\nSenescenc
 e and cancer - role and therapeutic opportunities. Schmitt CA\, Wang B\, D
 emaria M. Nat Rev Clin Oncol. 2022 Oct\;19(10):619-636. doi: 10.1038/s4157
 1-022-00668-4. Epub 2022 Aug 31. PMID: 36045302
ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/Marco
 _Demaria.png
CATEGORIES:Events in English,Tapahtumat
LOCATION:Arje Scheinin lecture hall\, Dentalia\, Lemminkäisenkatu 2\, Turk
 u\, Finland
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