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UID:366@inflames.utu.fi
DTSTART;TZID=Europe/Helsinki:20241002T120000
DTEND;TZID=Europe/Helsinki:20241002T130000
DTSTAMP:20240916T131757Z
URL:https://inflames.utu.fi/events/biocity-turku-guest-seminar-prof-makoto
 -suematsu/
SUMMARY:BioCity Turku Guest Seminar: Prof. Makoto Suematsu
DESCRIPTION:2nd October at 12:00\nOnsite event\nin Presidentti auditorium\,
  BioCity\n\nProf. Makoto Suematsu\, Keio University WPI-Bio2Q Research Cen
 ter\nImaging metabolomics in humanized experimental platforms: Translation
  to control cancer and neurodegenerative diseases\n\nHost: Bilal Andrabi (
 sbaand@utu.fi)\n\nCoffee and sandwich at 11:45. First come first served!\n
 \n&nbsp\;\n\nImaging metabolomics provides multi-dimensional imaging infor
 mation and includes imaging mass spectroscopy (IMS)\, surface-enhanced Ram
 an spectroscopy (SERS) and magnetic resonance imaging and spectroscopy (MR
 I/MRS). Two-dimensional visualization of small molecular metabolites in ca
 ncer or ischemic damages by IMS and SERS require rapid frozen protocols to
  get meaningful interpretation in experimental medicine. We have utilized 
 super-immunodeficient NOG mice which allow engraftment of patient-derived 
 cells or tissues to examine alterations in metabolic systems in vivo by IM
 S or SERS (1-4). These techniques also benefit clinical application of nee
 dle-biopsied or post-operative frozen tissue to predict prognosis of solid
  cancers (3\, 4). We have recently set up imaging metabolomics technology 
 to examine development of patient-derived cancer cells or neural disease m
 odels in mice or common marmoset\, a non-human primate (5-7): Among them\,
  ultra-high field MRI (UHF-MRI) which enables to chase time history of spa
 tio-temporal alterations in disease regions without euthanasia. I would li
 ke to introduce the “humanized” experimental platforms and to discuss 
 how to apply these methods for future collaboration.\n\n&nbsp\;\n\nSelecte
 d publications\n\nKubo A\, et al. Antioxidants (2023)\nParas M\, et al. Sc
 ience (2024)\nYamamoto T\, et al. Cancer Research (2024)\nSato K\, et al. 
 Lab Animal (2024)\n\n&nbsp\;\n\nBioCity Turku Guest Seminars are Frontiers
  of Science -level events with world-famous scientists giving the talks. T
 he speakers are distinguished scientists in their own field of research an
 d they invoke interest among the wide audience. This BioCity Turku Guest S
 eminar is organized by BioCity Turku\, Turku Bioscience Centre and InFLAME
 S Flagship.\n\n&nbsp\;
ATTACH;FMTTYPE=image/jpeg:https://inflames.utu.fi/wp-content/uploads/sumem
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CATEGORIES:Events in English,Tapahtumat
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